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KMID : 0378019700130020058
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New Medical Journal
1970 Volume.13 No. 2 p.58 ~ p.66
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Bacteriological Study of Infections in the Orthopedic Field
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Abstract
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From Sep. 1964 to Aug. 1968, 170 cases of infections in orthopedic field were studied and presented in Department of Orthopedic Surgery, Severance Hospital..
The 170 cases were: 120 cases of osteomyelitis, 16 cases of pyogenic arthritis, 15 cases of myositis and 37 cases of infected open wounds. The strains isolated from the lesions totaled 203.
The order of frequency of pyogenic organisms was summarized as follows: Staphylococcus 65%,*seudomonas 8.4%, E. coli 5.4%, Gram(-)bacillus 5.4%, Aerobacter 4.9%, Streptococcus 3.4%, ´Gram ( # ) coccus 3%, Proteus 1.5%, Salmonella 1.5%, Paracolon bacillus 1% and Gram(-) Coccobacillus 0. 5 %. A sensitivity test of various organisms was done by the single paper disc method.
The results were summarized as follows:
1) The most probable agent, staphylococci were highly resistant to penicillin(72. 3%) and most sensitive to albamycin(93. 1%) and relatively sensitive to various new antibiotics including leucomycin, erythromycin and terramycin.
2) The infections due to streptococci totaled only 7 cases in 203 strains and were sensitive to erythromycin, albamycin, leucomycin and highly resistant to penicillin and streptomycin.
3) The next probable agent to staphylococcus was pseudomonas (8.5%) and in most of the instances, pseudomonas was found in infected open wounds. pseudomonas was highly resistant to various antibiotics and slightly sensitive to tetracycline and kanamycin.
4) E. coli consisted of 5.4% of a total of 203 isolated strains and was highly resistant to various antibiotics and only slightly sensitive to sigmamycin, kanamycin, tetracycline and chloramphenicol.
5) It is emphasized that successful antibiotic chemotherapy can be carried out by avoidance of abuse or overuse of antibiotics, and by sufficient use of antibiotics, according to sensitivity tests, in adequate dosage and duration for complete cure.
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